ABSTRACT
Background and aims: COVID-19 is the disease caused by the SARS-CoV-2 coronavirus. The involvement of the infection at the respiratory level is clearly established. However, its neurological manifestations are less well known. Methods: A 43-year-old male patient consulted for symmetric and global weakness of the four limbs of progressive intensity with inability to ambulation, as well as alteration in the sensitivity of the four limbs at the distal level. 10 days earlier, she had had a self-limited episode of diarrhea, followed by symptoms of an upper respiratory infection. Results: The neurological examination revealed weakness of the four limbs and universal areflexia. The chest X-ray shows changes suggestive of incipient pneumonia due to COVID-19. SARS-CoV-2 PCR positivity is obtained. The conduction EMG study shows an increase in distal motor latencies and a decrease in sensory conduction velocities, as well as an increase in the minimum latency of the F wave for the right L5 and S1 roots, suggestive of demyelinating polyradiculoneuritis and compatible with the clinical suspicion of GBS. Conclusion: The possibility of infection by SARS-CoV-2 is considered as a cause of GBS, however, it is prudent to assess chance in its presentation. The association between COVID-19 and GBS is not established, however, several cases have recently been reported that suggest the participation of the virus in its etiopathogenesis. It is important and necessary to deepen the study of the neurological manifestations of SARS-CoV-2.